The Ley lab studies atherosclerosis, the pathomechanism underlying most cardiovascular disease. We focus on the adaptive immune system. We work on the autoimmune aspect of atherosclerosis, mainly on the CD4 and CD8 T cell responses.
Klaus Ley, M.D.
Founding Co-Director, Immunology Center of Georgia (IMMCG)
Georgia Research Alliance Bradley Turner Eminent Scholar in Immunology
Professor, Department of Physiology
Medical College of Georgia at 酴圖傻弝け
The lab uses human samples from patients with the disease we study: cardiovascular disease including coronary artery disease. Major methods we use:
Immunology Center of Georgia (IMMCG)
Health Sciences Campus
1410 Laney Walker Blvd, CN2119
706-446-0296
Anusha Bellapu
India
Michael Nakama, MS
United States of America
Pei Xiong Liew, PhD
Singapore
Mikhail Fomin, MSc
United States of America
Smriti Parashar, PhD
India
Sunil Kumar, Ph.D.
India
Yan Wang, PhD
China
Megh Mehta
United States of America
Aderonke Fakayode
Nigeria
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Gosavi, D. & , May 2025, In: Nature Cardiovascular Research. 4, 5, p. 500-502 3 p. Research output: Contribution to journal Comment/debate peer-review |
Wu, Y., Cao, Z., Liu, W., Cahoon, J. G., Wang, K., Wang, P., Hu, L., Chen, Y., Moser, M., Vella, A. T., , Wen, L. & Fan, Z., Dec 2025, In: Cell Communication and Signaling. 23, 1, 12. Research output: Contribution to journal Article peer-review |
Nettersheim, F. S., Brunel, S., Sinkovits, R. S., Armstrong, S. S., Roy, P., Billitti, M., Kobiyama, K., Alimadadi, A., , Lu, L., Zoccheddu, M., Oliaeimotlagh, M., Benedict, C. A., Sette, A. & , Jan 2025, In: Nature Immunology. 26, 1, p. 105-115 11 p., 812769. Research output: Contribution to journal Article peer-review |
Suthahar, S. S. A., Nettersheim, F. S., Alimadadi, A., Wang, E., Billitti, M., Resto-Trujillo, N., Roy, P., , & , Sep 1 2024, In: Cardiovascular Research. 120, 13, p. 1577-1589 13 p. Research output: Contribution to journal Article peer-review |
Sl羹tter, B. & , 2024, In: Frontiers in immunology. 15, 1440283. Research output: Contribution to journal Editorial peer-review |
Frias-Anaya, E., Gallego-Gutierrez, H., Gongol, B., Weinsheimer, S., Lai, C. C., , Sriram, A., Bui, C. M., Nelsen, B., Hale, P., Pham, A., Shenkar, R., Debiasse, D., Lightle, R., Girard, R., Li, Y., Srinath, A., Daneman, R., Nudleman, E. & Sun, H. & 8 others, , Jun 1 2024, In: Arteriosclerosis, thrombosis, and vascular biology. 44, 6, p. 1246-1264 19 p. Research output: Contribution to journal Article peer-review |
Roy, P., Suthahar, S. S. A., Makings, J. & , 2024, In: Frontiers in immunology. 15, 1302031. Research output: Contribution to journal Article peer-review |
Khan, A. & , Jul 2024, In: Cell Research. 34, 7, p. 467-468 2 p. Research output: Contribution to journal Article peer-review |
Stroope, C., Nettersheim, F. S., Coon, B., Finney, A. C., Schwartz, M. A., , Rom, O. & Yurdagul, A., Apr 2024, In: Nature Metabolism. 6, 4, p. 617-638 22 p. Research output: Contribution to journal Review article peer-review |
Gazzi, A., Fusco, L., , Keshavan, S., Shin, Y., Grivel, J. C., Rinchai, D., Ahmed, E. I., Elhanani, O., Furesi, G., Rauner, M., Keren, L., , Casiraghi, C., Bedognetti, D., Fadeel, B. & Delogu, L. G., Feb 2024, In: Nano Today. 54, 102084. Research output: Contribution to journal Article peer-review |
Chatterjee, N., , Durant, C. P., Wu, R., McSkimming, C., Drago, F., Kumar, S., Valentin-Guillama, G., Miller, Y. I., McNamara, C. A., , Taylor, A., Alimadadi, A. & , Mar 2024, In: International journal of molecular sciences. 25, 5, 2894. Research output: Contribution to journal Article peer-review |
Khan, A., Roy, P. & , Sep 2024, In: Nature Reviews Immunology. 24, 9, p. 670-679 10 p. Research output: Contribution to journal Article peer-review |
Pattarabanjird, T., Srikakulapu, P., Ransegnola, B., Marshall, M. A., Ghosheh, Y., Gulati, R., Durant, C., Drago, F., Taylor, A. M., & McNamara, C. A., 2023, In: Frontiers in immunology. 14, 1296668. Research output: Contribution to journal Article peer-review |
Iqneibi, S., Saigusa, R., Khan, A., Oliaeimotlagh, M., Armstrong Suthahar, S. S., Kumar, S., Alimadadi, A., Durant, C. P., Ghosheh, Y., McNamara, C. A., & , 2023, In: Frontiers in immunology. 14, 1239148. Research output: Contribution to journal Article peer-review |
Kiss, M. G., Papac-Milievi, N., Porsch, F., Tsiantoulas, D., Hendrikx, T., Takaoka, M., Dinh, H. Q., Narzt, M. S., G繹derle, L., Ozsv獺r-Kozma, M., Schuster, M., Fortelny, N., Hladik, A., Knapp, S., Gruber, F., Pickering, M. C., Bock, C., Swirski, F. K., & Zernecke, A. & 4 others, , Aug 8 2023, In: Immunity. 56, 8, p. 1809-1824.e10 Research output: Contribution to journal Article peer-review |
Slysz, J., Sinha, A., DeBerge, M., Singh, S., Avgousti, H., Lee, I., Glinton, K., Nagasaka, R., Dalal, P., Alexandria, S., Wai, C. M., Tellez, R., Vescovo, M., Sunderraj, A., Wang, X., Schipma, M., Sisk, R., Gulati, R., Vallejo, J. & Saigusa, R. & 8 others, , 2023, In: JCI Insight. 8, 17, e171359. Research output: Contribution to journal Article peer-review |
Lyu, Q., Wang, Y. & , Aug 2023, In: Journal of Leukocyte Biology. 114, 2, p. 109-110 2 p. Research output: Contribution to journal Editorial peer-review |
Pattarabanjird, T., Nguyen, A. T., McSkimming, C., Dinh, H. Q., Marshall, M. A., Ghosheh, Y., Gulati, R., Durant, C., Vallejo, J., Saigusa, R., Drago, F., Guy, T. V., Premo, K., Taylor, A. M., Paul, S., Kundu, B., Berr, S., Gonen, A., Tsimikas, S. & Miller, Y. & 4 others, , Dec 2023, In: Nature Cardiovascular Research. 2, 12, p. 1328 1 p. Research output: Contribution to journal Comment/debate peer-review |
Pattarabanjird, T., Wilson, J. M., Erickson, L. D., Workman, L. J., Qiao, H., Ghosheh, Y., Gulati, R., Durant, C., Vallejo, J., Saigusa, R., Platts-Mills, T. A. E., Taylor, A. M., & McNamara, C. A., 2021, In: Frontiers in Cardiovascular Medicine. 8, 791028. Research output: Contribution to journal Article peer-review |
Nettersheim, F. S., Braumann, S., Kobiyama, K., , Vassallo, M., Miller, J., Ali, A., Roy, P., Saigusa, R., Wolf, D., & Winkels, H., 2021, In: Frontiers in Cardiovascular Medicine. 8, 812769. Research output: Contribution to journal Article peer-review |
Pattarabanjird, T., Nguyen, A. T., McSkimming, C., Dinh, H. Q., Marshall, M. A., Ghosheh, Y., Gulati, R., Durant, C., Vallejo, J., Saigusa, R., Drago, F., Guy, T. V., Premo, K., Taylor, A. M., Paul, S., Kundu, B., Berr, S., Gonen, A., Tsimikas, S. & Miller, Y. & 4 others, , Nov 2023, In: Nature Cardiovascular Research. 2, 11, p. 1003-1014 12 p. Research output: Contribution to journal Article peer-review |
Freuchet, A., Roy, P., Armstrong, S. S., Oliaeimotlagh, M., Kumar, S., , Ali, A. J., Khan, A., Makings, J., Lyu, Q., Winkels, H., Wang, E., Durant, C., Ghosheh, Y., Gulati, R., Nettersheim, F. & , Oct 2023, In: Nature Immunology. 24, 10, p. 1748-1761 14 p. Research output: Contribution to journal Article peer-review |
Saigusa, R., Roy, P., Freuchet, A., Gulati, R., Ghosheh, Y., Armstrong Suthahar, S. S., Durant, C. P., Hanna, D. B., Kiosses, W. B., , Wen, L., Wu, R., Kuniholm, M. H., Landay, A. L., Anastos, K., Tien, P. C., Gange, S. J., Kassaye, S., Vallejo, J. & & 5 others, , May 2022, In: Nature Cardiovascular Research. 1, 5, p. 462-475 14 p. Research output: Contribution to journal Article peer-review |
Wang, Z., Zhang, X., Lu, S., Zhang, C., Ma, Z., Su, R., Li, Y., Sun, T., Li, Y., Hong, M., Deng, X., Rafiee Monjezi, M., Hristov, M., Steffens, S., Santovito, D., Dornmair, K., , Weber, C., Mohanta, S. K. & Habenicht, A. J. R. & 1 others, , Mar 2023, In: Nature Cardiovascular Research. 2, 3, p. 290-306 17 p. Research output: Contribution to journal Article peer-review |
Zernecke, A., Erhard, F., Weinberger, T., Schulz, C., , Saliba, A. E. & Cochain, C., Jun 1 2023, In: Cardiovascular Research. 119, 8, p. 1676-1689 14 p. Research output: Contribution to journal Article peer-review |
Fusco, L., Gazzi, A., Shuck, C. E., , Ahmed, E. I., Giro, L., Zavan, B., Yilmazer, A., , Bedognetti, D., Gogotsi, Y. & Delogu, L. G., Aug 18 2023, In: Small Methods. 7, 8, 2300197. Research output: Contribution to journal Article peer-review |
Lin, J., Ehinger, E., Hanna, D. B., Qi, Q., Wang, T., Ghosheh, Y., Mueller, K., Anastos, K., Lazar, J. M., Mack, W. J., Tien, P. C., Berman, J. W., Cohen, M. H., Ofotokun, I., Gange, S., Liu, C., Heath, S. L., Tracy, R. P., Hodis, H. N. & Landay, A. L. & 2 others, , May 2023, In: PloS one. 18, 5 May, e0285926. Research output: Contribution to journal Article peer-review |
Lyu, Q. & , Feb 1 2023, In: Arteriosclerosis, thrombosis, and vascular biology. 43, 2, p. 215-217 3 p. Research output: Contribution to journal Editorial peer-review |
Nettersheim, F. S., Ghosheh, Y., Winkels, H., Kobiyama, K., Durant, C., Armstrong, S. S., Brunel, S., Roy, P., Dileepan, T., Jenkins, M. K., Zajonc, D. M. & , Jan 5 2023, In: Frontiers in Cardiovascular Medicine. 9, 1076808. Research output: Contribution to journal Article peer-review |
Li, W., Wen, L., Rathod, B., Gingras, A. C., & Lee, H. S., Mar 1 2023, In: Life Science Alliance. 6, 3 Research output: Contribution to journal Article peer-review |
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